Cargando…

Post-meiotic DNA double-strand breaks occur in Tetrahymena, and require Topoisomerase II and Spo11

Based on observations of markers for DNA lesions, such as phosphorylated histone H2AX (γH2AX) and open DNA ends, it has been suggested that post-meiotic DNA double-strand breaks (PM-DSBs) enable chromatin remodeling during animal spermiogenesis. However, the existence of PM-DSBs is unconfirmed, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akematsu, Takahiko, Fukuda, Yasuhiro, Garg, Jyoti, Fillingham, Jeffrey S, Pearlman, Ronald E, Loidl, Josef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482572/ https://www.ncbi.nlm.nih.gov/pubmed/28621664 http://dx.doi.org/10.7554/eLife.26176

Ejemplares similares

Resistance to 6-Methylpurine is Conferred by Defective Adenine Phosphoribosyltransferase in Tetrahymena
por: Akematsu, Takahiko, et al.
Publicado: (2018)

Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of Tetrahymena thermophila
por: Akematsu, Takahiko, et al.
Publicado: (2014)

The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena
por: Akematsu, Takahiko, et al.
Publicado: (2019)

Snf2 Proteins Are Required to Generate Gamete Pronuclei in Tetrahymena thermophila
por: Fukuda, Yasuhiro, et al.
Publicado: (2022)

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11
por: Faieta, Monica, et al.
Publicado: (2015)

Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination
por: Fukuda, Tomoyuki, et al.
Publicado: (2008)

A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation
por: Tian, Miao, et al.
Publicado: (2018)

Functional Proteomics of Nuclear Proteins in Tetrahymena thermophila: A Review
por: Saettone, Alejandro, et al.
Publicado: (2019)

A Single Cohesin Complex Performs Mitotic and Meiotic Functions in the Protist Tetrahymena
por: Howard-Till, Rachel A., et al.
Publicado: (2013)

Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila
por: Nabeel-Shah, Syed, et al.
Publicado: (2021)

Arrested crossover precursor structures form stable homologous bonds in a Tetrahymena meiotic mutant
por: Tian, Miao, et al.
Publicado: (2022)

Gene Network Landscape of the Ciliate Tetrahymena thermophila
por: Xiong, Jie, et al.
Publicado: (2011)

Meiotic chromosome dynamics and double strand break formation in reptiles
por: Marín-Gual, Laia, et al.
Publicado: (2022)

BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena
por: Shodhan, Anura, et al.
Publicado: (2017)

Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity
por: Guo, Heyun, et al.
Publicado: (2022)

Mapping meiotic breaks: Spo11 oligonucleotides precisely mark the spots
por: Hwang, Patty Yi-Hwa, et al.
Publicado: (2011)

Mechanism and Control of Meiotic DNA Double-Strand Break Formation in S. cerevisiae
por: Yadav, Vikash Kumar, et al.
Publicado: (2021)

Role of apoptosis-inducing factor (AIF) in programmed nuclear death during conjugation in Tetrahymena thermophila
por: Akematsu, Takahiko, et al.
Publicado: (2010)

The meiotic topoisomerase VI B subunit (MTOPVIB) is essential for meiotic DNA double-strand break formation in barley (Hordeum vulgare L.)
por: Steckenborn, Stefan, et al.
Publicado: (2022)

Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila
por: Lake, Cathleen M, et al.
Publicado: (2015)

Tetrahymena meiosis: Simple yet ingenious
por: Loidl, Josef
Publicado: (2021)

Exploring the Histone Acetylation Cycle in the Protozoan Model Tetrahymena thermophila
por: Wahab, Suzanne, et al.
Publicado: (2020)

Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila
por: Nabeel-Shah, Syed, et al.
Publicado: (2020)

Rad9, a 53BP1 Ortholog of Budding Yeast, Is Insensitive to Spo11-Induced Double-Strand Breaks During Meiosis
por: Usui, Takehiko, et al.
Publicado: (2021)

The Recombinases Rad51 and Dmc1 Play Distinct Roles in DNA Break Repair and Recombination Partner Choice in the Meiosis of Tetrahymena
por: Howard-Till, Rachel A., et al.
Publicado: (2011)

Proteomic Analysis of Histones H2A/H2B and Variant Hv1 in Tetrahymena thermophila Reveals an Ancient Network of Chaperones
por: Ashraf, Kanwal, et al.
Publicado: (2019)

The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay
por: Shingu, Yoshinori, et al.
Publicado: (2012)

ATM controls meiotic double-strand break formation
por: Lange, Julian, et al.
Publicado: (2011)

The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila
por: Saettone, Alejandro, et al.
Publicado: (2018)

Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair
por: Johnson, Rebecca, et al.
Publicado: (2007)

Meiotic Genes and DNA Double Strand Break Repair in Cancer
por: Lingg, Lea, et al.
Publicado: (2022)

SPoRE: a mathematical model to predict double strand breaks and axis protein sites in meiosis
por: Champeimont, Raphaël, et al.
Publicado: (2014)

NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis
por: Zhang, Bin, et al.
Publicado: (2020)

Condensins promote chromosome individualization and segregation during mitosis, meiosis, and amitosis in Tetrahymena thermophila
por: Howard-Till, Rachel, et al.
Publicado: (2018)

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114
por: Sasanuma, Hiroyuki, et al.
Publicado: (2007)

Divergent patterns of meiotic double strand breaks and synapsis initiation dynamics suggest an evolutionary shift in the meiosis program between American and Australian marsupials
por: Valero-Regalón, F. Javier, et al.
Publicado: (2023)

Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination
por: Sansam, Christopher L, et al.
Publicado: (2015)

Comprehensive dissection of meiotic DNA double-strand breaks and crossovers in cucumber
por: Wang, Yanling, et al.
Publicado: (2023)

A specialized condensin complex participates in somatic nuclear maturation in Tetrahymena thermophila
por: Howard-Till, Rachel, et al.
Publicado: (2019)

A Topoisomerase II Inhibitor, NK109, Induces DNA Single‐ and Double‐strand Breaks and Apoptosis
por: Fukuda, Minoru, et al.
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_1k185876n24nhbl4urrgj5fu30