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9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments

COPI coated vesicles mediate trafficking within the Golgi apparatus and between the Golgi and the endoplasmic reticulum. Assembly of a COPI coated vesicle is initiated by the small GTPase Arf1 that recruits the coatomer complex to the membrane, triggering polymerization and budding. The vesicle unco...

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Detalles Bibliográficos
Autores principales: Dodonova, Svetlana O, Aderhold, Patrick, Kopp, Juergen, Ganeva, Iva, Röhling, Simone, Hagen, Wim J H, Sinning, Irmgard, Wieland, Felix, Briggs, John A G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482573/
https://www.ncbi.nlm.nih.gov/pubmed/28621666
http://dx.doi.org/10.7554/eLife.26691