Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones

Chronic Lymphocytic Leukemia (CLL) is a lymphoproliferative disorder with either indolent or aggressive clinical course. Current treatment regiments have significantly improved the overall outcomes even if higher risk subgroups - those harboring TP53 mutations or deletions of the short arm of chromo...

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Detalles Bibliográficos
Autores principales: Carrà, Giovanna, Panuzzo, Cristina, Torti, Davide, Parvis, Guido, Crivellaro, Sabrina, Familiari, Ubaldo, Volante, Marco, Morena, Deborah, Lingua, Marcello Francesco, Brancaccio, Mara, Guerrasio, Angelo, Pandolfi, Pier Paolo, Saglio, Giuseppe, Taulli, Riccardo, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482594/
https://www.ncbi.nlm.nih.gov/pubmed/28418900
http://dx.doi.org/10.18632/oncotarget.16348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482594/
https://www.ncbi.nlm.nih.gov/pubmed/28418900
http://dx.doi.org/10.18632/oncotarget.16348

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