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Activation of α(1A)-adrenergic receptor promotes differentiation of rat-1 fibroblasts to a smooth muscle-like phenotype
BACKGROUND: Fibroblasts, as connective tissue cells, are able to transform into another cell type including smooth muscle cells. α(1A)-adrenergic receptor (α(1A)-AR) stimulation in rat-1 fibroblasts is coupled to cAMP production. However, the significance of an increase in cAMP produced by α(1A)-AR...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548263/ https://www.ncbi.nlm.nih.gov/pubmed/15603588 http://dx.doi.org/10.1186/1471-2121-5-47 |