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BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population

Pancreatic cancer is a highly lethal disease with limited prognostic marker. BRAC1 and BRCA2 are two classic tumor suppressor genes which play an important role in DNA repair. Somatic mutations and germline genetic variants on BRCA1/2 have been found associated with the tumorigenesis of pancreatic c...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Zhai, Kan, Ke, Juntao, Li, Jiaoyuan, Gong, Yajie, Yang, Yang, Tian, Jianbo, Zhang, Yi, Zou, Danyi, Peng, Xiating, Gong, Jing, Zhong, Rong, Huang, Kun, Chang, Jiang, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482636/
https://www.ncbi.nlm.nih.gov/pubmed/28415599
http://dx.doi.org/10.18632/oncotarget.16422