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ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression

Previously we found that the estrogen receptor (ER) related factor ERRF regulates cell proliferation and tumor growth, and its expression is positively associated with ER status and better survival but inversely associated with ERBB2 (also named HER2) status in breast cancer. Here we report that ERR...

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Detalles Bibliográficos
Autores principales: Qi, Leilei, Zhang, Baotong, Zhang, Shiying, Ci, Xinpei, Wu, Qiao, Ma, Gui, Luo, Ang, Fu, Liya, King, Jamie L., Nahta, Rita, Dong, Jin-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482638/
https://www.ncbi.nlm.nih.gov/pubmed/28415602
http://dx.doi.org/10.18632/oncotarget.16425