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Inhibiting G protein βγ signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel

Aberrant activation of G protein-coupled receptors (GPCRs) is implicated in prostate cancer progression, but targeting them has been challenging because multiple GPCRs are involved in cancer progression. In this study, we tested the effect of blocking signaling via a hub through which multiple GPCRs...

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Detalles Bibliográficos
Autores principales: Paudyal, Prakash, Xie, Qing, Vaddi, Prasanna Kuma, Henry, Michael D., Chen, Songhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482639/
https://www.ncbi.nlm.nih.gov/pubmed/28415604
http://dx.doi.org/10.18632/oncotarget.16428