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Inhibiting G protein βγ signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel
Aberrant activation of G protein-coupled receptors (GPCRs) is implicated in prostate cancer progression, but targeting them has been challenging because multiple GPCRs are involved in cancer progression. In this study, we tested the effect of blocking signaling via a hub through which multiple GPCRs...
Autores principales: | Paudyal, Prakash, Xie, Qing, Vaddi, Prasanna Kuma, Henry, Michael D., Chen, Songhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482639/ https://www.ncbi.nlm.nih.gov/pubmed/28415604 http://dx.doi.org/10.18632/oncotarget.16428 |
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