Identification of driver modules in pan-cancer via coordinating coverage and exclusivity

It is widely accepted that cancer is driven by accumulated somatic mutations during the lifetime of an individual. Cancer mutations may target relatively small number of cell functional modules. The heterogeneity in different cancer patients makes it difficult to identify driver mutations or functio...

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Detalles Bibliográficos
Autores principales: Gao, Bo, Li, Guojun, Liu, Juntao, Li, Yang, Huang, Xiuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482642/
https://www.ncbi.nlm.nih.gov/pubmed/28415609
http://dx.doi.org/10.18632/oncotarget.16433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482642/
https://www.ncbi.nlm.nih.gov/pubmed/28415609
http://dx.doi.org/10.18632/oncotarget.16433

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