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Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing

The aim of this study was to profile somatic mutation spectrum in gallbladder cancers (GBCs), and determine the role of MAP kinase pathway in GBC by a series of in vitro and in vivo studies. We performed targeted massively parallel sequencing of DNA isolated from GBCs and matched blood from 14 GBC p...

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Detalles Bibliográficos
Autores principales: Li, Mengdan, Chen, Lihong, Qu, Yiping, Sui, Fang, Yang, Qi, Ji, Meiju, Shi, Bingyin, Chen, Mingwei, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482657/
https://www.ncbi.nlm.nih.gov/pubmed/28422736
http://dx.doi.org/10.18632/oncotarget.16751