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Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing
The aim of this study was to profile somatic mutation spectrum in gallbladder cancers (GBCs), and determine the role of MAP kinase pathway in GBC by a series of in vitro and in vivo studies. We performed targeted massively parallel sequencing of DNA isolated from GBCs and matched blood from 14 GBC p...
Autores principales: | Li, Mengdan, Chen, Lihong, Qu, Yiping, Sui, Fang, Yang, Qi, Ji, Meiju, Shi, Bingyin, Chen, Mingwei, Hou, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482657/ https://www.ncbi.nlm.nih.gov/pubmed/28422736 http://dx.doi.org/10.18632/oncotarget.16751 |
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