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Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer

Wnt signal pathway genes are known to be involved with cancer development. Here we tested the hypothesis whether DNA methylation of genes part of the Wnt signaling pathway could help the diagnosis of non-small cell lung cancer (NSCLC). The methylation levels of SFRP1, SFRP2, WIF1 and PRKCB in 111 NS...

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Detalles Bibliográficos
Autores principales: Liu, Shunlin, Chen, Xiaoying, Chen, Ruhua, Wang, Jinzhi, Zhu, Guoliang, Jiang, Jianzhong, Wang, Hongwei, Duan, Shiwei, Huang, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482660/
https://www.ncbi.nlm.nih.gov/pubmed/28422739
http://dx.doi.org/10.18632/oncotarget.16754