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Parkin regulates translesion DNA synthesis in response to UV radiation

Deficiency of Parkin is a major cause of early-onset Parkinson's disease (PD). Notably, PD patients also exhibit a significantly higher risk in melanoma and other skin tumors, while the mechanism remains largely unknown. In this study, we show that depletion of Parkin causes compromised cell vi...

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Detalles Bibliográficos
Autores principales: Zhu, Xuefei, Ma, Xiaolu, Tu, Yingfeng, Huang, Min, Liu, Hongmei, Wang, Fengli, Gong, Juanjuan, Wang, Jiuqiang, Li, Xiaoling, Chen, Qian, Shen, Hongyan, Zhu, Shu, Wang, Yun, Liu, Yang, Guo, Caixia, Tang, Tie-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482665/
https://www.ncbi.nlm.nih.gov/pubmed/28430587
http://dx.doi.org/10.18632/oncotarget.16855