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Parkin regulates translesion DNA synthesis in response to UV radiation
Deficiency of Parkin is a major cause of early-onset Parkinson's disease (PD). Notably, PD patients also exhibit a significantly higher risk in melanoma and other skin tumors, while the mechanism remains largely unknown. In this study, we show that depletion of Parkin causes compromised cell vi...
Autores principales: | Zhu, Xuefei, Ma, Xiaolu, Tu, Yingfeng, Huang, Min, Liu, Hongmei, Wang, Fengli, Gong, Juanjuan, Wang, Jiuqiang, Li, Xiaoling, Chen, Qian, Shen, Hongyan, Zhu, Shu, Wang, Yun, Liu, Yang, Guo, Caixia, Tang, Tie-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482665/ https://www.ncbi.nlm.nih.gov/pubmed/28430587 http://dx.doi.org/10.18632/oncotarget.16855 |
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