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Cyclic-RGDyC functionalized liposomes for dual-targeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy study

The efficacy of boron neutron capture therapy depends on the selective delivery of (10)B to the target. Integrins αvβ3 are transmembrane receptors over-expressed in both glioblastoma cells and its neovasculature. In this study, a novel approach to dual-target glioblastoma vasculature and tumor cells...

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Detalles Bibliográficos
Autores principales: Kang, Weirong, Svirskis, Darren, Sarojini, Vijayalekshmi, McGregor, Ailsa L., Bevitt, Joseph, Wu, Zimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482681/
https://www.ncbi.nlm.nih.gov/pubmed/28402271
http://dx.doi.org/10.18632/oncotarget.16625