Insulin growth factor binding protein 2 mediates the progression of lymphangioleiomyomatosis

Lymphangioleiomyomatosis (LAM) is a progressive pulmonary disease that almost exclusively affects women. LAM cells migrate to the lungs, where they cause cystic destruction of lung parenchyma. Mutations in TSC1 or TSC2 lead to the activation of the mammalian target of rapamycin complex-1, a kinase t...

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Detalles Bibliográficos
Autores principales: Li, Xiangke, Liu, Xiaolei, Zhang, Linda, Li, Chenggang, Zhang, Erik, Ma, Wang, Fan, Qingxia, Yu, Jane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482682/
https://www.ncbi.nlm.nih.gov/pubmed/28410230
http://dx.doi.org/10.18632/oncotarget.16695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482682/
https://www.ncbi.nlm.nih.gov/pubmed/28410230
http://dx.doi.org/10.18632/oncotarget.16695

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