Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget

The various sphingosine kinase (SphK) isoenzymes (isozymes) and isoforms, key players in normal cellular physiology, are strongly implicated in cancer and other diseases. Mutations in SphKs, that may justify abnormal physiological function, have not been recorded. Nonetheless, there is a large and g...

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Detalles Bibliográficos
Autores principales: Hatoum, Diana, Haddadi, Nahal, Lin, Yiguang, Nassif, Najah T., McGowan, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482707/
https://www.ncbi.nlm.nih.gov/pubmed/28415564
http://dx.doi.org/10.18632/oncotarget.16370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482707/
https://www.ncbi.nlm.nih.gov/pubmed/28415564
http://dx.doi.org/10.18632/oncotarget.16370

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