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A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC

Our previous work identified a 13-gene miRNA signature predictive of response to the epidermal growth factor receptor (EGFR) inhibitor, erlotinib, in Non-Small Cell Lung Cancer cell lines. Bioinformatic analysis of the signature showed a functional convergence on TGFβ canonical signalling. We hypoth...

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Detalles Bibliográficos
Autores principales: Krentz Gober, Madeline, Collard, James P., Thompson, Katherine, Black, Esther P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482799/
https://www.ncbi.nlm.nih.gov/pubmed/28646226
http://dx.doi.org/10.1038/s41598-017-04097-7