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A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC
Our previous work identified a 13-gene miRNA signature predictive of response to the epidermal growth factor receptor (EGFR) inhibitor, erlotinib, in Non-Small Cell Lung Cancer cell lines. Bioinformatic analysis of the signature showed a functional convergence on TGFβ canonical signalling. We hypoth...
Autores principales: | Krentz Gober, Madeline, Collard, James P., Thompson, Katherine, Black, Esther P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482799/ https://www.ncbi.nlm.nih.gov/pubmed/28646226 http://dx.doi.org/10.1038/s41598-017-04097-7 |
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