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Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low survival rate. Targeting signal transduction pathways which promote therapy resistance and metastatic dissemi...

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Detalles Bibliográficos
Autores principales: Momeny, Majid, Zarrinrad, Ghazaleh, Moghaddaskho, Farima, Poursheikhani, Arash, Sankanian, Ghazaleh, Zaghal, Azam, Mirshahvaladi, Shahab, Esmaeili, Fatemeh, Eyvani, Haniyeh, Barghi, Farinaz, Sabourinejad, Zahra, Alishahi, Zivar, Yousefi, Hassan, Ghasemi, Reza, Dardaei, Leila, Bashash, Davood, Chahardouli, Bahram, Dehpour, Ahmad R., Tavakkoly-Bazzaz, Javad, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir, Ghaffari, Seyed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482808/
https://www.ncbi.nlm.nih.gov/pubmed/28646172
http://dx.doi.org/10.1038/s41598-017-04147-0