Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques

In vivo electroporation (EP) is used to enhance the uptake of nucleic acids and its association with DNA vaccination greatly stimulates immune responses to vaccine antigens delivered through the skin. However, the effect of EP on cutaneous cell behavior, the dynamics of immune cell recruitment and l...

Descripción completa

Detalles Bibliográficos
Autores principales: Todorova, Biliana, Adam, Lucille, Culina, Slobodan, Boisgard, Raphaël, Martinon, Frédéric, Cosma, Antonio, Ustav, Mart, Kortulewski, Thierry, Le Grand, Roger, Chapon, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482824/
https://www.ncbi.nlm.nih.gov/pubmed/28646234
http://dx.doi.org/10.1038/s41598-017-04547-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482824/
https://www.ncbi.nlm.nih.gov/pubmed/28646234
http://dx.doi.org/10.1038/s41598-017-04547-2

Ejemplares similares