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Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling

HAART is very effective in suppressing HIV-1 replication in patients. However, patients staying on long-term HAART still develop various HIV-associated neurological disorders, even when the viral load is low. The underlying pathogenic mechanisms are largely unknown. Emerging evidence implicated that...

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Detalles Bibliográficos
Autores principales:	Wu, Ting, Zhang, Juan, Geng, Mingxing, Tang, Shao-Jun, Zhang, Wenping, Shu, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482870/ https://www.ncbi.nlm.nih.gov/pubmed/28646196 http://dx.doi.org/10.1038/s41598-017-03446-w

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