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IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration

Disc degeneration (DD) is a multifaceted chronic process that alters the structure and function of intervertebral discs. The pathophysiology of degeneration is not completely understood, but the consensus is that changes in genes encoding extracellular matrix (ECM) proteins in the disc are the leadi...

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Detalles Bibliográficos
Autores principales: Wang, Shengjie, Liu, Chao, Sun, Zhongyi, Yan, Peng, Liang, He, Huang, Kai, Li, Changwei, Tian, Jiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482889/
https://www.ncbi.nlm.nih.gov/pubmed/28646230
http://dx.doi.org/10.1038/s41598-017-04384-3