Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells

BACKGROUND: Disorders of the oxidative phosphorylation (OXPHOS) system represent a large group among the inborn errors of metabolism. The most frequently observed biochemical defect is isolated deficiency of mitochondrial complex I (CI). No effective treatment strategies for CI deficiency are so far...

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Detalles Bibliográficos
Autores principales: Melcher, Marlen, Danhauser, Katharina, Seibt, Annette, Degistirici, Özer, Baertling, Fabian, Kondadi, Arun Kumar, Reichert, Andreas S., Koopman, Werner J. H., Willems, Peter H. G. M., Rodenburg, Richard J., Mayatepek, Ertan, Meisel, Roland, Distelmaier, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482938/
https://www.ncbi.nlm.nih.gov/pubmed/28646906
http://dx.doi.org/10.1186/s13287-017-0601-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482938/
https://www.ncbi.nlm.nih.gov/pubmed/28646906
http://dx.doi.org/10.1186/s13287-017-0601-7

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