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Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma

BACKGROUND: Asthma is a chronic inflammatory disease that can be difficult to treat due to its complex pathophysiology. Most current drugs focus on controlling the inflammatory process, but are unable to revert the changes of tissue remodeling. Human mesenchymal stromal cells (MSCs) are effective at...

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Detalles Bibliográficos
Autores principales: de Castro, Ligia Lins, Xisto, Debora Gonçalves, Kitoko, Jamil Zola, Cruz, Fernanda Ferreira, Olsen, Priscilla Christina, Redondo, Patricia Albuquerque Garcia, Ferreira, Tatiana Paula Teixeira, Weiss, Daniel Jay, Martins, Marco Aurélio, Morales, Marcelo Marcos, Rocco, Patricia Rieken Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482954/
https://www.ncbi.nlm.nih.gov/pubmed/28646903
http://dx.doi.org/10.1186/s13287-017-0600-8