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Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial

BACKGROUND: A randomized controlled trial of adults with empyema recently demonstrated decreased length of stay in hospital in patients treated with intrapleurally administered dornase alfa and fibrinolytics compared to fibrinolytics alone. Whether this treatment strategy is safe and effective in ch...

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Detalles Bibliográficos
Autores principales: Livingston, Michael H., Mahant, Sanjay, Ratjen, Felix, Connolly, Bairbre L., Thorpe, Kevin, Mamdani, Muhammad, Maclusky, Ian, Laberge, Sophie, Giglia, Lucy, Walton, J. Mark, Yang, Connie L., Roberts, Ashley, Shawyer, Anna C., Brindle, Mary, Parsons, Simon J., Stoian, Cristina A., Cohen, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482972/
https://www.ncbi.nlm.nih.gov/pubmed/28646887
http://dx.doi.org/10.1186/s13063-017-2026-0