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3D motion of vesicles along microtubules helps them to circumvent obstacles in cells

Vesicle transport is regulated at multiple levels, including regulation by scaffolding proteins and the cytoskeleton. This tight regulation is essential, since slowing or stoppage of transport can cause accumulation of obstacles and has been linked to diseases. Understanding the mechanisms by which...

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Detalles Bibliográficos
Autores principales: Verdeny-Vilanova, Ione, Wehnekamp, Fabian, Mohan, Nitin, Sandoval Álvarez, Ángel, Borbely, Joseph Steven, Otterstrom, Jason John, Lamb, Don C., Lakadamyali, Melike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482975/
https://www.ncbi.nlm.nih.gov/pubmed/28420672
http://dx.doi.org/10.1242/jcs.201178