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The secreted MSP domain of C. elegans VAPB homolog VPR-1 patterns the adult striated muscle mitochondrial reticulum via SMN-1

The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotrophic lateral sclerosis. Secreted MSPds derived from the C. elegans VAPB homolog VPR-1 promote mitochondrial localization to actin-rich I-bands in body wall muscle. Here we show that the nervous system...

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Detalles Bibliográficos
Autores principales: Schultz, Jessica, Lee, Se-Jin, Cole, Tim, Hoang, Hieu D., Vibbert, Jack, Cottee, Pauline A., Miller, Michael A., Han, Sung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482996/
https://www.ncbi.nlm.nih.gov/pubmed/28634272
http://dx.doi.org/10.1242/dev.152025