Cargando…
The secreted MSP domain of C. elegans VAPB homolog VPR-1 patterns the adult striated muscle mitochondrial reticulum via SMN-1
The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotrophic lateral sclerosis. Secreted MSPds derived from the C. elegans VAPB homolog VPR-1 promote mitochondrial localization to actin-rich I-bands in body wall muscle. Here we show that the nervous system...
Autores principales: | Schultz, Jessica, Lee, Se-Jin, Cole, Tim, Hoang, Hieu D., Vibbert, Jack, Cottee, Pauline A., Miller, Michael A., Han, Sung Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482996/ https://www.ncbi.nlm.nih.gov/pubmed/28634272 http://dx.doi.org/10.1242/dev.152025 |
Ejemplares similares
-
The C. elegans VAPB homolog VPR-1 is a permissive signal for gonad development
por: Cottee, Pauline A., et al.
Publicado: (2017) -
VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in Caenorhabditis elegans
por: Han, Sung Min, et al.
Publicado: (2013) -
Sequestosome 1 Is Part of the Interaction Network of VAPB
por: James, Christina, et al.
Publicado: (2021) -
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle
por: Rajendra, T.K., et al.
Publicado: (2007) -
Structural, Stability, Dynamic and Binding Properties of the ALS-Causing T46I Mutant of the hVAPB MSP Domain as Revealed by NMR and MD Simulations
por: Lua, Shixiong, et al.
Publicado: (2011)