Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

Sphingolipidoses are inherited diseases belonging to the class of lysosomal storage diseases (LSDs), which are characterized by the accumulation of indigestible material in the lysosome caused by specific defects in the lysosomal degradation machinery. While some LSDs can be efficiently treated by e...

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Detalles Bibliográficos
Autores principales: Sellin, Julia, Schulze, Heike, Paradis, Marie, Gosejacob, Dominic, Papan, Cyrus, Shevchenko, Andrej, Psathaki, Olympia Ekaterina, Paululat, Achim, Thielisch, Melanie, Sandhoff, Konrad, Hoch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483003/
https://www.ncbi.nlm.nih.gov/pubmed/28389479
http://dx.doi.org/10.1242/dmm.027953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483003/
https://www.ncbi.nlm.nih.gov/pubmed/28389479
http://dx.doi.org/10.1242/dmm.027953

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