Paneth-cell-disruption-induced necrotizing enterocolitis in mice requires live bacteria and occurs independently of TLR4 signaling

Necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality in premature infants. Both human surgical specimens and animal models suggest a potential involvement of Paneth cells in NEC pathogenesis. Paneth cells play critical roles in epithelial homeostasis, innate immunity an...

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Detalles Bibliográficos
Autores principales: White, Jessica R., Gong, Huiyu, Pope, Brock, Schlievert, Patrick, McElroy, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483007/
https://www.ncbi.nlm.nih.gov/pubmed/28450472
http://dx.doi.org/10.1242/dmm.028589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483007/
https://www.ncbi.nlm.nih.gov/pubmed/28450472
http://dx.doi.org/10.1242/dmm.028589

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