Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes

Long QT syndrome (LQTS) is characterized by a prolonged QT-interval on electrocardiogram and by increased risk of sudden death. One of the most common and potentially life-threatening electrolyte disturbances is hypokalemia, characterized by low concentrations of K(+). Using a multielectrode array p...

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Detalles Bibliográficos
Autores principales: Kuusela, Jukka, Larsson, Kim, Shah, Disheet, Prajapati, Chandra, Aalto-Setälä, Katriina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483019/
https://www.ncbi.nlm.nih.gov/pubmed/28619993
http://dx.doi.org/10.1242/bio.024216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483019/
https://www.ncbi.nlm.nih.gov/pubmed/28619993
http://dx.doi.org/10.1242/bio.024216

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