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Akt3 is responsible for the survival and proliferation of embryonic stem cells

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt) pathway plays an important role in regulating cell proliferation, metabolism, and survival. However, the distinct roles of Akt isoforms (Akt1, Akt2, and Akt3) in pluripotent stem cell maintenance are not fully defined. Using mouse e...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Huang, Delun, Jiang, Zongliang, Luo, Yan, Norris, Carol, Zhang, Ming, Tian, Xiuchun, Tang, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483023/
https://www.ncbi.nlm.nih.gov/pubmed/28483982
http://dx.doi.org/10.1242/bio.024505