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Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation

Protein inhibitor of activated Stat 3 (Pias3) is implicated in guiding specification of rod and cone photoreceptors through post-translational modification of key retinal transcription factors. To investigate its role during retinal development, we deleted exon 2-5 of the mouse Pias3 gene, which res...

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Detalles Bibliográficos
Autores principales: Campla, Christie K., Breit, Hannah, Dong, Lijin, Gumerson, Jessica D., Roger, Jerome E., Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483026/
https://www.ncbi.nlm.nih.gov/pubmed/28495965
http://dx.doi.org/10.1242/bio.024679