Heme molecule functions as an endogenous agonist of astrocyte TLR2 to contribute to secondary brain damage after intracerebral hemorrhage

Toll-like receptor 2 (TLR2) was recently shown to contribute to secondary brain damage after intracerebral hemorrhage (ICH), although the molecular mechanisms of this contribution are elusive. In this study, we tested the hypothesis that hemin functions as a TLR2 endogenous agonist, causing proinfla...

Descripción completa

Detalles Bibliográficos
Autores principales: Min, Hyunjung, Choi, Boomin, Jang, Yong Ho, Cho, Ik-Hyun, Lee, Sung Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483261/
https://www.ncbi.nlm.nih.gov/pubmed/28646881
http://dx.doi.org/10.1186/s13041-017-0305-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483261/
https://www.ncbi.nlm.nih.gov/pubmed/28646881
http://dx.doi.org/10.1186/s13041-017-0305-z

Ejemplares similares