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Role of P2X(7)R in the development and progression of pulmonary hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a devastating disease that lacks sufficient treatment. Studies have shown that the Nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome contributes to PAH pathogenesis, but the role of the upstream molecular P2X(7) receptor (P2...

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Detalles Bibliográficos
Autores principales: Yin, Jie, You, Shuling, Liu, Haopeng, Chen, Li, Zhang, Chengdong, Hu, Hesheng, Xue, Mei, Cheng, Wenjuan, Wang, Ye, Li, Xinran, Shi, Yugen, Li, Nannan, Yan, Suhua, Li, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483271/
https://www.ncbi.nlm.nih.gov/pubmed/28646872
http://dx.doi.org/10.1186/s12931-017-0603-0