Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation

T helper-17 (Th17) cells are associated with inflammatory disorders and cancer. We report that environmental conditions resulting in cellular stress, such as low oxygen, glucose, and isotonic stress, particularly enhance the generation of Th17 cells. Pharmacological inhibition of cell stress reduces...

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Detalles Bibliográficos
Autores principales: Brucklacher-Waldert, Verena, Ferreira, Cristina, Stebegg, Marisa, Fesneau, Olivier, Innocentin, Silvia, Marie, Julien C., Veldhoen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483510/
https://www.ncbi.nlm.nih.gov/pubmed/28614720
http://dx.doi.org/10.1016/j.celrep.2017.05.052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483510/
https://www.ncbi.nlm.nih.gov/pubmed/28614720
http://dx.doi.org/10.1016/j.celrep.2017.05.052

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