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Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms
Pore-forming proteins play critical roles in pathogenic attack and immunological defence. The membrane attack complex/perforin (MACPF) group of homologues represents, with cholesterol-dependent cytolysins, the largest family of such proteins. In this review, we begin by describing briefly the struct...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483515/ https://www.ncbi.nlm.nih.gov/pubmed/28630152 http://dx.doi.org/10.1098/rstb.2016.0212 |