A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III–IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId

The hepatitis C virus (HCV) has a positive single-stranded RNA genome, and translation starts within the internal ribosome entry site (IRES) in a cap-independent manner. The IRES is well conserved among HCV subtypes and has a unique structure consisting of four domains. We used an in vitro selection...

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Detalles Bibliográficos
Autores principales: Kikuchi, Kunio, Umehara, Takuya, Fukuda, Kotaro, Kuno, Atsushi, Hasegawa, Tsunemi, Nishikawa, Satoshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548359/
https://www.ncbi.nlm.nih.gov/pubmed/15681618
http://dx.doi.org/10.1093/nar/gki215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548359/
https://www.ncbi.nlm.nih.gov/pubmed/15681618
http://dx.doi.org/10.1093/nar/gki215

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