Limited TTP supply affects telomere length regulation in a telomerase-independent fashion

An adequate supply of nucleotides is essential for DNA replication and DNA repair. Moreover, inhibition of TTP synthesis can cause cell death by a poorly characterized mechanism called thymine-less death. In the yeast Saccharomyces cerevisiae, the genes encoding thymidylate synthetase (CDC21) and th...

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Detalles Bibliográficos
Autores principales: Toussaint, Martin, Dionne, Isabelle, Wellinger, Raymund J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548361/
https://www.ncbi.nlm.nih.gov/pubmed/15681620
http://dx.doi.org/10.1093/nar/gki219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548361/
https://www.ncbi.nlm.nih.gov/pubmed/15681620
http://dx.doi.org/10.1093/nar/gki219

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