Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat encoding an abnormally long polyglutamine tract (PolyQ) in the huntingtin (Htt) protein. In HD, striking neuropathological changes occur in the striatum, including loss...

Descripción completa

Detalles Bibliográficos
Autores principales: Morigaki, Ryoma, Goto, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483636/
https://www.ncbi.nlm.nih.gov/pubmed/28590448
http://dx.doi.org/10.3390/brainsci7060063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483636/
https://www.ncbi.nlm.nih.gov/pubmed/28590448
http://dx.doi.org/10.3390/brainsci7060063

Ejemplares similares