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Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat encoding an abnormally long polyglutamine tract (PolyQ) in the huntingtin (Htt) protein. In HD, striking neuropathological changes occur in the striatum, including loss...

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Detalles Bibliográficos
Autores principales:	Morigaki, Ryoma, Goto, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483636/ https://www.ncbi.nlm.nih.gov/pubmed/28590448 http://dx.doi.org/10.3390/brainsci7060063

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