Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts

Replication origins are licensed for a single initiation event by the loading of Mcm2-7 proteins during late mitosis and G1. Sequential associations of origin recognition complex, Cdc6 and Mcm2-7 are essential for completion of the licensing. Although Cdt1 also binds to the chromatin when the licens...

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Detalles Bibliográficos
Autores principales: Tsuyama, Takashi, Tada, Shusuke, Watanabe, Saori, Seki, Masayuki, Enomoto, Takemi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548366/
https://www.ncbi.nlm.nih.gov/pubmed/15687385
http://dx.doi.org/10.1093/nar/gki226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548366/
https://www.ncbi.nlm.nih.gov/pubmed/15687385
http://dx.doi.org/10.1093/nar/gki226

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