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Diagnosis of HNF-1α mutations on a PNA zip-code microarray by single base extension

In the present study, we exploited the superior features of peptide nucleic acids (PNAs) to develop an efficient PNA zip-code microarray for the detection of hepatocyte nuclear factor-1α (HNF-1α) mutations that cause type 3 maturity onset diabetes of the young (MODY). A multi-epoxy linker compound w...

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Detalles Bibliográficos
Autores principales: Song, Jae Yang, Park, Hyun Gyu, Jung, Sung-Ouk, Park, JaeChan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548378/
https://www.ncbi.nlm.nih.gov/pubmed/15687377
http://dx.doi.org/10.1093/nar/gni020