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Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma

Despite improvements in therapeutic strategies, glioblastoma (GB) remains one of the most lethal cancers. The presence of the blood–brain barrier, the infiltrative nature of the tumor and several resistance mechanisms account for the failure of current treatments. Distinct DNA repair pathways can ne...

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Detalles Bibliográficos
Autores principales: Annovazzi, Laura, Mellai, Marta, Schiffer, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483876/
https://www.ncbi.nlm.nih.gov/pubmed/28587121
http://dx.doi.org/10.3390/cancers9060057