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Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain Cancer

The PI3K pathway is one of the most highly perturbed cell signaling pathways in human cancer, including the most common malignant brain tumors, gliomas, where either activating mutations of positive pathway effectors or loss/inactivation of pathway inhibitors occurs. Knowledge of the precise transcr...

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Detalles Bibliográficos
Autor principal: Mantamadiotis, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483879/
https://www.ncbi.nlm.nih.gov/pubmed/28556811
http://dx.doi.org/10.3390/cancers9060060