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Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein Biomarkers

Aptamers are nucleic acids referred to as chemical antibodies as they bind to their specific targets with high affinity and selectivity. They are selected via an iterative process known as ‘selective evolution of ligands by exponential enrichment’ (SELEX). Aptamers have been developed against numero...

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Detalles Bibliográficos
Autores principales: Mercier, Marie-Cécile, Dontenwill, Monique, Choulier, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483888/
https://www.ncbi.nlm.nih.gov/pubmed/28635657
http://dx.doi.org/10.3390/cancers9060069