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Magnetic poly(2-hydroxyethyl methacrylate) microspheres for affinity purification of monospecific anti-p46 kDa/Myo1C antibodies for early diagnosis of multiple sclerosis patients

The aim of the present study is to develop new magnetic polymer microspheres with functional groups available for easy protein and antibody binding. Monodisperse macroporous poly(2-hydroxyethyl methacrylate) (PHEMA-COOH) microspheres ~4 µm in diameter and containing ∼1 mmol COOH/g were synthesized b...

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Detalles Bibliográficos
Autores principales: Horák, Daniel, Hlídková, Helena, Kit, Yurii, Antonyuk, Volodymyr, Myronovsky, Severyn, Stoika, Rostyslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484020/
https://www.ncbi.nlm.nih.gov/pubmed/28351895
http://dx.doi.org/10.1042/BSR20160526