Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor

Conotoxins are a pool of disulfide-rich peptide neurotoxins produced by cone snails for predation and defense. They are a rich reservoir of novel ligands for ion channels, neurotransmitter receptors and transporters in the nervous system. In this study, we identified a novel conotoxin component, O-c...

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Detalles Bibliográficos
Autores principales: Jiang, Shantong, Tae, Han-Shen, Xu, Shaoqiong, Shao, Xiaoxia, Adams, David J., Wang, Chunguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484120/
https://www.ncbi.nlm.nih.gov/pubmed/28598389
http://dx.doi.org/10.3390/md15060170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484120/
https://www.ncbi.nlm.nih.gov/pubmed/28598389
http://dx.doi.org/10.3390/md15060170

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