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Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and SDF-1

The marine origin polysaccharide fucoidan combines multiple biological activities. As demonstrated by various studies in vitro and in vivo, fucoidans show anti-viral, anti-tumor, anti-oxidant, anti-inflammatory and anti-coagulant properties, although the detailed molecular action remains to be eluci...

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Detalles Bibliográficos
Autores principales: Wang, Fanlu, Schmidt, Harald, Pavleska, Dijana, Wermann, Thees, Seekamp, Andreas, Fuchs, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484136/
https://www.ncbi.nlm.nih.gov/pubmed/28632184
http://dx.doi.org/10.3390/md15060186